PROTOZOA 193 



Negri Bodies (Negri, 1903). Origin. Found in the 

 nervous system of animals dying of rabies (hydrophobia) . 



Form. Round and oval, hyaline bodies, with a sharp outline 

 and containing a nucleolus. The plasma is slightly granular. 

 They are regarded as protozoa. 



Staining. A smear from brain tissue is made on a cover- 

 glass and fixed in methyl-alcohol for five minutes; then stained 

 by Giemsa; stain for half -hour to three hours. 



Spirillum of Relapsing Fever (Obermeier, 1873). Syn- 

 onym. Spirochaeta Obermeieri. 



Fig. 118. Spirochaeta Obermeieri from human blood (Kolle and Wasser- 



mann). 



The definite classification of this organism has not been 

 made. Some regard it now as a protozoon, and one of a group 

 in which numerous other spirilla belong. 



Origin. Found in the blood of recurrent fever patients, 

 described in 1873. 



Form. Long, wavy threads (16 to 40 // long), a true spiril- 

 lum; flagella are present (Fig. 118). 



Properties. Very motile. Has not been cultivated. 



Staining. Ordinary anilin stains. Bismarck-brown best 

 for tissue sections. 



Pathogenesis. Found in the organs and blood of recurrent 

 fever. Man and monkeys inoculated with blood from one suf- 

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