PREFACE TO THE FIFTH EDITION 



THIS little book has had such a gratifying recep- 

 tion at the hands of physicians and students that 

 no change either in scope or plan has been made in 

 the present edition. The entire. material has, how- 

 ever, undergone a careful revision. Because of the 

 repeated demands for information regarding the 

 making of Wassermann tests, it has been deemed 

 advisable to describe in detail the technique em- 

 ployed under the supervision of one of the writers 

 in the Serological Laboratory of the New York City 

 Department of Health. 



CHARLES BOLDUAN. 



NEW YORK, April, 1917. 



PREFACE TO THE FOURTH EDITION 



THE favorable reception accorded to the previous 

 editions of this book, together with the fact that 

 our knowledge of the subject has increased con- 

 siderably in the past few years, has led the author 

 to undertake a thorough revision of the work. 



In its first edition, in 1904, this book dealt only 

 with certain antibodies whose discovery had aroused 



