XI. LEUCOCYTE EXTRACTS IN THE TREAT- 

 MENT OF INFECTIONS 



Theory .Attention has already been called to 

 Hiss's view concerning the role of leucocytes in 

 combating infections. Believing that the phagocytic 

 power of leucocytes of persons suffering from infec- 

 tions to be less than that of leucocytes of. the normal 

 individual, Hiss was led to extract these cells with 

 a view to utilizing their neutralizing and other pro- 

 tective substances in readily diffusible form. By 

 this means it was thought possible to furnish to the 

 infected organism such assistance as would enable 

 its phagocytic cells to properly protect the various 

 tissues from poisons elaborated from the invading 

 bacteria. 



Preparation of the Extracts. In the preparation of 

 the extract, double pleural inoculations of aleuronat * 

 suspensions are made into rabbits. After 24 hours 

 the rabbits are killed and the turbid fluid collected 

 from both pleural cavities. The quantity obtained 

 varies from about 30 to 60 cc. The fluid is quickly 

 centrifuged and the serum decanted. The cells are 



1 Aleuronat, a vegetable product similar to gluten, is pre- 

 pared by Hundhausen, in Hamm, Westphalia, Germany, and 

 is supplied in packages containing 100 grams. The suspensions 

 are prepared with thin starch paste and boiled. 



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