DYSENTERIC AM(EB/E CORRELATED 159 



of division, and to the variation in the number of 

 divisions undergone by the organism prior to its 

 assumption of the resting form. E. minuta thus 

 originated. Finally the budding phenomena de- 

 scribed by Schaudinn were traced and found to be 

 of a degenerative nature. 



What, then, should be the proper title of the 

 organism around which so much discussion has 

 raged ? On the score of priority, the name E. histo- 

 lytica supersedes that of E. tetragena and E. minuta 

 a course that is regrettable, since it was from 

 laborious researches on E. tetragena that the life- 

 cycle was elaborated, and some of the great confu- 

 sion regarding the pathogenic Entamcebae of man 

 was removed. 



Another amoeba associated with dysentery in 

 Japanese has been named E. nipponica. It was found 

 together with E. histolytica, and, like it, is capable 

 of devouring red blood-corpuscles, which are found 

 within it. The nucleus contains a karyosome, and 

 so is like the " tetragena " form of E. histolytica. 

 Multiplication is by division into two, or repeated 

 division of the nucleus into six or eight can take 

 place, so that six or eight merozoites are ultimately 

 formed. Prior to encystment some of the chromatin 

 is expelled from the nucleus into the cytoplasm. 

 Darling considers that E. nipponica is a form of 

 E. histolytica (E. tetragena). A recent paper by Akashi 

 suggests that E. nipponica is not a true parasite, but 

 that epithelial cells were mistaken for amoebae in 

 such cases. 



Other Amoebae from the alimentary canal of man 



