CHANCES WROUGHT IN PATHOLOGY, / tot 



between changes in the physical stdte o$ ; colloids ;ari( t 'the 

 changes which go on in living matter. It would, however, 

 be unfair to expect such a principle to hold quantitatively 

 for every biological detail. It is subject rather to the 

 various changes brought about through differences in 

 living matter which vary with different kinds of animals 

 and with different kinds of organs. While calcium, 

 strontium, and barium have an almost equal effect in 

 the presence of sulphocyanates on egg albumin in a 

 test-tubej the synergistic function of the barium is the 

 most apparent of the three in a physiological experiment 

 on the heart. In a similar way LOEB and HERBST 

 found that individual differences exist between ions in 

 their effect upon different marine animals. Nevertheless, 

 the general law governing all these phenomena appears 

 everywhere, at one time more, at another time less dis- 

 tinctly, just as in a musical composition the theme is 

 heard at all times by him who has once learned it among 

 the infinite number of its variations. 



6. Changes Wrought in Pathology through Advances 

 in Physical Chemistry.* 



NOT until it has been found possible to explain the 

 anomalies in the functions of the organism through 

 changes in the form and in the composition of its constit- 

 uents can pathology consider its task completed. Its field 

 of knowledge grows in three ways: through the experi- 



* Wandlungen in der Pathologic durch die Fortschritte der all- 

 gemeinen Chemie, Wien, 1905. Festival address at the third annual 

 meeting of the K. k. Gesellschaft der Aerzte in Vienna, March 24, 1905. 



