314 THERAPEUTICAL EFFECTS 



but neither sulpho-carbolic, nor carbolic acid, was 

 evident to tests. The flesh showed a marked ten- 

 dency to resist putrefaction. 



Dr. Sansom found that 20 grain doses of sodium 

 sulpho-carbolate could be readily administered to 

 adults. The dose was increased in some cases to 60 

 grains administered every four hours. The only direct 

 effect noted was a slight vertigo or dizziness. The 

 odour of carbolic acid could be readily detected in 

 the breath. The urine of a patient, who had taken 

 360 grains of sodium sulpho-carbolate in 24 hours 

 was collected and examined. It presented no evidence 

 of the presence of carbolic acid, but contained a con- 

 siderable quantity of sodium sulphate. It resisted 

 putrefaction. 



It would appear, therefore, that sodium sulpho- 

 carbolate administered to a living animal is rapidly 

 absorbed and carried throughout the system. In the 

 blood, or the tissues, the double salt is decomposed, 

 the sodium sulphate being set free in the tissues, and 

 ultimately excreted by the kidneys. The carbolic 

 acid also liberated in the textures, for the most part 

 escapes by the lungs. It is probable, also, that some 

 portion of the carbolic acid is eliminated by the 

 urine. The administration of sodium sulpho-carbolate 

 is, therefore, an indirect means of introducing carbo- 

 lic acid ; and, inasmuch as at least one-fourth of the 

 weight of the sulpho-carbolate employed consists of 

 carbolic acid, we find that an amount of the latter 



