410 FOOD AND DIGESTION 



a. Observe two kinds of intestinal movements, segmenting movements 

 of the intestine, and peristaltic movements, i.e., rings of contractions 

 moving downward. Compare these movements carefully, noting the 

 rate of propagation, the sequence, etc. 



b. Note especially the movements of the stomach. Compare the 

 pylorus with the fundus. Where does peristalsis commence in the cat 

 stomach? 



c. Insert a stomach tube and fill with warm water until distended, 

 record any reactions. 



d. Stimulate the vagus in the neck with interrupted induction shocks 

 of moderate intensity. 



e. Cut the splanchnics, then stimulate the vagus again. Explain the 

 variations. 



/. Inject i cc. of a o.i per cent, nicotine solution intravenously, 

 explain. 



g. Inject i cc. of o.i per cent, epinephrin. 



28. Pancreatic and Bile Secretion. Anesthetize and tracheotomize 

 a dog and connect with the ether apparatus. Expose the jugular for 

 venous injections. Ligate the vagus on the same side and section. 

 Open the abdomen along the upper half of the linea alba, 6 or 8 inches. 

 Expose the duodenum and insert a cannula into the common bile duct 

 at the point where it joins the intestine. The greater pancreatic duct 

 along the posterior border of the pancreas enters the intestine below the 

 bile duct. Carefully dissect and insert a cannula. Provide all the can- 

 nulae with small rubber tubes long enough to extend to the surface through 

 the wound. Carefully adjust the parts and close the wound by stitches. 



a. Record the rate of pancreatic and bile secretions by signal key. 



b. Stimulate the peripheral end of the vagus in the neck. Give time 

 for recovery from the vascular effects and for the secretion to develop. 



c. Inject 20 to 30 cc. of 0.4 per cent, hydrochloric acid by hypodermic 

 needle into the duodenum. The reaction is slow. Allow 15 minutes or 

 more and repeat. 



d. Inject 40 cc. of "secretin" solution prepared by extracting the 

 macerated mucosa of the duodenum with 0.4 per cent. HC1 and 

 neutralizing carefully and filtering. Secretin is in solution in the 

 filtrate. Repeat in 20 to 30 minutes (Journal of Physiology, Vol. 28, 

 P- 2 35> 1920). Read the topic of chemical control and hormones. 



