Carbolic Acid. 41 



Results obtained after standing eighteen hours : 

 No. 1. Only a very slight discoloration. 

 No. 2. Dark brown deposit. 

 No. 3. Still darker discoloration. 

 No. 4. Black deposit. 



Other similar experiments were made on two other 

 dogs, with precisely the same results, which seem to 

 show that the sulphurous acid is not all, by any means, 

 used up in the pulmonary circuit. 



Carbolic Acid. 



At this time, carbolic acid was largely used as an 

 antiseptic and disinfectant. It was further stated, that 

 it destroyed parasites, both animal and vegetable, and 

 that it arrested fermentation. I therefore (October 14, 

 1869) made the following solution : 



Pure solid carbolic acid (Calvert's) 3 parts. 

 Distilled water - 1 



Glycerine - 12 ,, 



So that m. xxv equalled 47 grains of carbolic acid. 



EXPERIMENT I. 



I injected into the femoral vein of a small dog 

 m. xxv. 



Result. Within a few minutes, a tremor com- 

 menced in all the muscles, which passed into clonic 

 spasms all over the body, from the eye-lids to the tail. 

 The dog remained quite sensible, and in five minutes 

 the spasms ceased. Five minutes afterwards, another 



