TttE REGULATION Of GASTRIC SECRETION. 205 



fact it has been shown experimentally by SSANOZKI that 

 merely tempting a dog with food often leads to a greater secre- 

 tion of gastric juice in the unit of time than the actual sham 

 feeding. 



The "appetite juice" varies both in quantity and quality. 

 The more eagerly a dog eats the greater the amount of juice 

 and the higher the digestive power. A good appetite at the 

 beginning of a meal is, therefore, equal to a copious secre- 

 tion of strong gastric juice. > 



5. The Physiological Importance of the Appetite Juice. 

 It was shown above that the secretion of gastric juice during 

 the first hour is practically the same for meat or bread, and 

 that only subsequently the amount and quality of the gastric 

 secretion varies with the nature of the ingested food. When 

 only sham feeding with these same foods is indulged in, we find 

 that the secretion of juice for the first hour is the same as 

 though the dog had been actually fed. All this indicates* 

 that the first outpouring of juice into the stomach at the/ 

 beginning of a meal is^the consequence of the psychic excita- 

 tion. The truth of this statement is still further borne out 

 by the fact that when a food is given the* dog which does not 

 interest him to the same degree as meat or bread, for example, 

 milk, this initial rise in the quantity and quality of the gas- 

 tric juice does not appear. While 12.4 c.c. of gastric juice, 

 having a digestive power of 5.43 mm., are poured out upon 

 meat, and 13.4 c.c., having a digestive power of 5.37 mm., 

 are poured out upon bread during the first hour after feeding, 

 only 4.2 c.c. of a digestive power of 3.57 mm. are poured out 

 upon milk (CHIGIN). That the mere act of taking food in- 

 creases both the quantity and quality of the gastric juice 

 is still further supported by the observation of KOTLJAR and 

 LOBASSOFF, who found that when an ordinary meal is divided 

 into several portions, and these are fed at intervals of three 

 hours, an increase in the quantity and quality of the juice 

 immediately follows each installment. > 



The role of the appetite juice can be still more clearly 



