442 BACILLI WHICH PRODUCE SEPTICAEMIA 



succumbed to such an injection the bacilli were not generally dis- 

 tributed in the tissues, but were found as emboli in the smaller capil- 

 laries. This bacillus, then, is distinguished from the similar bacilli 

 previously described (Nbs. Gl and 63) by its comparatively slight 

 pathogenic power, as well as by its more vigorous growth in culture 

 media, and the other characters heretofore mentioned. 



66. BACILLUS SEPTICUS AGRIGENUS. 



Obtained by Nicolaier from soil which had been manured. 



Moiphology. Resembles the bacillus of fowl cholera and of rabbit sep- 

 ticaemia, of which it is perhaps a variety, but is usually somewhat longer. 

 It also sometimes shows the end-staining characteristic of Bacillus septicse- 

 miae haemorrhagicae, but not so constantly and not so sharply defined. 



Biological Characters. An aerobic, (non liquefying ?), non- motile ba- 

 cillus. Does not form spores. 



In gelatin plate cultures spherical, finely granular colonies are developed 

 having a yellowish-brown central portion, which is separated by a dark 

 ring from a grayish brown marginal zone; later this difference in color dis- 

 appears and the colonies become more decidedly granular. In stick cultures 

 tne growth consists of a thin layer which is not at all characteristic. 



Pathogenesis. Small quantities of a pure culture injected into the ear 

 vein of a rabbit cause its death in from twenty-four to thirty six hours; 

 pathogenic also for house mice and for field mice. At the autopsy no notable 

 pathological changes are observed. The bacilli are found in blood from the 

 neart and in the capillaries of the various organs, but are not so numerous 

 as in rabbit septicaemia; they show a special inclination to adhere to the 

 margins of the red blood corpuscles. 



67. BACILLUS ERYSIPELATOS SUIS. 



Synonyms. Bacillus of hog erysipelas; Bacillus des Schweine- 

 rothlauf (Loffler, Schiitz) ; Bacille du rouget du pore (Pasteur) ; Ba- 

 cillus of mouse septicaemia; Bacillus murisepticus (Flugge) ; Bacil- 

 lus des Mauseseptikamie (Koch). 



The bacillus of mouse septicaemia, first described by Koch (1878), 

 resembles so closely in its morphology, characters of growth, and 

 pathogenic power the bacillus of Schweinerothlauf of Loffler and 

 Schiitz (1885) that they can scarcely be considered as distinct spe- 

 cies, although, from slight differences which have been observed, they 

 are perhaps entitled to separate consideration as varieties of the 

 same species. Fliigge, Eisenberg, Frankel, and other authors, while 

 recognizing the fact that the bacilli from the two sources closely re- 

 semble each other, apparently do not consider them identical, and 

 describe them separately. Baumgarten, on the other hand, describes 

 them under one heading and considers it highly probable that they 

 are identical, although he also admits slight differences in the 

 morphological characters and growth in culture media. These 

 differences are, however, no greater than we have in artificially pro- 

 duced varieties of other well-known microorganisms, and we think 



