512 PATHOGENIC AEROBIC BACILLI 



149. STREPTOCOCCUS CONGLOMERATE (Kurth). 



Obtained by Kurth (1890) from cases of scarlet fever. 



Morphology. As obtained from bouillon cultures it consists of masses 

 made up of chains of cocci; free chains are only occasionally seen. 



Biological Characters. This streptococcus is said to differ from Strepto- 

 coccus pyogenes and various other previously described streptococci by the 

 fact that in bouillon cultures, at a temperature of 37 C. , it forms at the bot- 

 tom of the tube smooth, round, and very firm white scales, or a single flat 

 layer which is not disintegrated when the tube is slightly agitated ; other 

 streptococci are said to form a loose deposit which is either entirely broken 

 up or forms viscid threads when the tube is gently rotated. 



Pathogenesis. Very pathogenic for mice. * 



150. BACILLUS CAPSULATUS Mucosus (Fasching). 



Obtained from the nasal secretion in two cases of influenza. 



Morphology. Bacilli from 3 to 4 /* long and 0.75 to 1 /* thick, enveloped 

 in a capsule containing one to four individuals. 



Biological Characters. An aerobic and facultative anaerobic, non- 

 motile, non-liquefying bacillus. Does not form spores. Grows in the usual 

 culture media at 18 to 35 C. Upon gelatin plates circular, milk-white colo- 

 nies are developed ; these have a faint aromatic odor and are cupped upon 

 the upper surface ; they resemble drops of mucus about the size of a pin's head. 

 In stick cultures in gelatin a nail-like growth, like that of Friedlander's bacil- 

 lus, is seen, and there is a formation of gas. 



Stains with the usual aniline colors, but not by Gram's method. 



Pathogenesis. White mice and field mice die from general infection in 

 from thirty-six to forty-eight hours after inoculation ; they also suffer from 

 conjunctivitis. Not pathogenic for rabbits or for pigeons. 



151. BACILLUS PYOGENES SOLI. 



Obtained by Bolton from garden earth by inoculation into a rat. Found 

 in association with the tetanus bacillus in pus from the inoculation wound. 



Morphology. Closely resembles the bacillus of diphtheria. " It presents 

 the same irregularities of shape, and the transverse, unstained clear spares 

 in stained preparations, as the diphtheria bacillus. The individual bacilli 

 vary greatly in length and thickness, and many of them are bent and nar- 

 rower through the middle than at the poles." 



Stains readily with the usual aniline colors, but takes the stain irregularly, 

 sometimes showing deeply stained spots which may be perfectly round. Does 

 not stain by Gram's method. 



Biological Characters. An aerobic and facultative anaerobic, non- 

 Uquefying, non-motile bacillus. Spore formation not observed with cer- 

 tainty highly refractive ovoid bodies are sometimes met with, but these do 

 not seem to be specially resistant to heat. In gelatin roll tubes very small, 

 spherical colonies are developed, which under a low power are seen to !>< 

 finely granular and to have a lemon-yellow color. Grows best in a slight 1 y 

 acid medium very slowly at the room temperature. In gelatin stick cul- 

 tures isolated colonies are formed along the line of puncture. Scanty growt h 

 on potato or blood serum. Bolton says : " I have rarely succeeded in getting 

 a growth in agar." 



Pathogenesis. Subcutaneous inoculations in rats, gray mice, rabbits, 

 and usually in white mice produce an abscess at the point of inoculation. 

 Injections into the ear veins of rabbits sometimes give rise to multiple ab- 

 scesses, especially in the joints and kidneys. " The abscesses following sub- 

 cutaneous inoculation form very quickly, within twenty-four hours, and run 



