BACTERIA IN INFECTIOUS DISEASES. 593 



GAS PHLEGMON. 



In four cases of so-called gas phlegmon Frankel (E.) found an anaerobic 

 bacillus named by him Bacillus phlegmones emphysematosse. Cultures of 

 this bacillus gave rise to a similar process when injected subcutaneously 

 in guinea-pigs. In a case reported by Bunge (1894) Bacillus coli com- 

 munis is believed to have been the infectious agent to which the develop- 

 ment of the gas phlegmon was due. 



GLANDERS. 



Due to infection by Bacillus mallei (No. 56). 



GONORRHOEA. 



Due to infection by Micrococcus gonorrhoeas (No. 6) "Gono- 

 coccus" of Neisser. 



GRANULOMA FUNGOIDES (MYCOSIS FUNGOIDES). 



Rindfleisch (1885) and Auspitz (1885) report the presence of streptococci in 

 the capillary vessels of the papillary body and of the subcutaneous tissue in 

 the affected localities in cases of this disease. That the streptococcus differs 

 from Streptococcus pyogenes, as Auspitz supposes, has not been definitely 

 established. 



GROUSE DISEASE. 



See Bacillus of grouse disease, of Klein (No. 76). 



HOG CHOLERA. 



Due to infection by a motile bacillus of the "colon group" 

 Bacillus of hog cholera, of Salmon and Smith (No. 63). 



HOG ERYSIPELAS. 



Due to infection by Bacillus erysipelatos suis (No. 67). 



HYDROPHOBIA. 



Notwithstanding the extended researches made, especially in Pasteur's 

 laboratory, the etiology of hydrophobia still remains unsettled. It has been 

 demonstrated by experiment that the virus of the disease is located in the 

 brain, spinal marrow, and nerves of animals which have succumbed to the 

 disease, as well as in the salivary secretions of rabid animals, and that the 

 disease may be transmitted by intravenous inoculation, or by introducing a 

 small quantity of virus beneath the dura mater, with greater certainty than 

 by subcutaneous inoculations. But the exact nature of this virus has not been 

 determined. The fact that a considerable interval elapses after inoculation 

 before the first symptoms are developed indicates that there is a multiplica- 

 tion of the virus in the body of the infected animal ; and this is further 

 shown by the fact that after death the entire brain and spinal marrow of the 

 animal have a virulence equal to that of the material with which it was in- 

 oculated in the first instance. The writer's experiments (1887) show that this 

 virulence is neutralized by a temperature of 60 C. maintained for ten min- 

 utesa temperature which is fatal to all known pathogenic bacteria in the 

 absence of spores. But recent experiments show that certain toxic products 



