596 BACTERIA IN INFECTIOUS DISEASES. 



tained from a case of keratomalacia a capsule bacillus resembling 

 that of Pfeiffer, wbich was pathogenic for mice and for guinea-pigs. 

 The bacillus of Friedlander has also been found by Etienue and by 

 Yerson and Gabrielides (1894) in "ulcus comas septicum." 



LEPROSY. 



No satisfactory experimental demonstration that the Bacillus 

 leprae is the cause of the disease with which it is associated has yet 

 been made ; but there is very little doubt among bacteriologists and 

 pathologists that such is the case. For the facts relating to its pres- 

 ence in leprous tissues, its morphology, etc., the reader is referred to 

 the descriptive account of Bacillus leprse (No. 53, page 394). 



LEUCOCYTH^KMIA. 



Pawlowsky (1892) in four cases of leucocythsemia found i the blood a 

 few short bacilli, with round ends, which showed polar staining (with 

 methylene blue solution). He did not succeed in cultivating them in the 

 usual media, but in a mixture of bouillon and blood serum a granular de- 

 posit was seen at the end of four days, and transplantation from this to gly- 

 cerin-agar (plates) gave colonies, at 37 C., in three or four days. These were 

 small, round, and of a grayish-yellow color. Inoculations in rabbits gave a 

 negative result. 



LUPUS. 



Due to infection by Bacillus tuberculosis (No. 53). 



MADURA FOOT. 



Le Dantec (1894) arrives at the conclusion that the variety of madura foot 

 in which the characteristic masses are black is probably due to a bacillus 

 found by him in these " grains." This bacillus differs from the streptothnx 

 previously described by Vincent, and supposed by him to be the cause of the 

 malady. It is difficult of cultivation, and inoculation experiments in rab- 

 bits and guinea-pigs gave a negative result. 



LYMPHANGITIS. 



Lymphangitis of the extremities, according to Verneuil and Clado, is due 

 to infection by Streptococcus pyogenes. Fiscner and Levy (1893) as a result 

 of their investigations arrive at a different conclusion. In 8 cases tlu-y 

 found Staphylococcus pyogenes albus in 5, Staphylococcus pyogenes am VMS 

 in 1, Bacillus coli communis in 1, Staphylococcus pyogenes aureus and 

 Staphylococcus pyogenes albus associated in 1. In abscesses following lym- 

 phangitis (8) Staphylococcus pyogenes albus was found in 4, Streptococcus 

 pyogenes in 2, Staphylococcus pyogenes albus and Staphylococcus pyogrm s 

 aureus associated in 1 ; Staphylococcus pyogenes albus and Streptococcus 

 pyogenes in 1. 



MALARIA. 



Klebs and Tommasi-Crudeli, as a result of researches made by then i in 

 the vicinity of Rome (18/9), announced the discovery of a bacillus which 

 they supposed to be the cause of malarial fevers their Bacillus malariae. 



