256 



THE ORGANS 



the parietal cells always maintain a connection with the lumen. 

 This is accomplished by means of little clefts between the chief cells, 

 intercellular secretory tubules, which extend down to the parietal cells, 

 ly means of the method of Golgi may be demonstrated not only the 

 intercellular secretory tubules, but also the fact that upon reaching the 

 cells these are continuous with a network of minute spaces within the 

 cell — the intracellular secretory tubicles (Figs. 158 and 159). Parietal 











^/-^ 



iiu^^^€ 



© 



c/i.m 



c 



. t^c.ft.m 



Fig. 158. — Sections through Different Parts of a Fundus Gland of Human Stomach. 



A, mouth of gland; cells resemble surface cells except that they are shorter. 



B, neck of gland; cp, principal cells; cpm, mucous cells; ch, parietal cells, one contain- 

 ing two nuclei. 



C, middle portion of gland; cp, chief cells; ch, parietal cells. 



D, deeper part of gland; cp, chief cells containing secretorj- granules, and at their 

 bases ergastoplasm filaments {erg) : at c are shown intracellular secretor}^ canals pene- 

 trating base of cell; cb, parietal cells, one of which shows canaliculus leading to lumen of 

 gland (i), the latter being cut twice in section owing to its irregulaf course. 



E, blind end of gland; cp, chief cells with secretion granules and ergastoplasm fila- 

 ments (erg); cb, parietal cells, one containing three nuclei; cpm, mucous cells; /, lumen of 

 gland. X250. (Prenant.) 



cells are not distributed uniformly throughout the gland, but are 

 most numerous in the body, where they frequently almost obscure 

 the chief cells. In the fundus of the gland parietal cells are less nu- 

 merous. For this reason and because of the wider lumen of the fundus, 

 transverse and longitudinal sections of this part of the tubule are 

 most satisfactory for the study of the relations of the two kinds of 

 cells (Figs. 156 and 157). Mitosis is most active at the junction of 

 the neck and body of the tubule which has consequently been desig- 

 nated the "growing point" of the tubule. 



