THE NERXOUS SYSTEM 



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In the cortex can be distinguished an outer or molecidar layer with 

 few cells and few mcdullated fibres, an inner, granular or nuclear 

 layer, and between the two a single row of large flask-shaped cells, 

 the cells of Piirkinje (Figs. 346, 347). These latter give off several 

 main dendrites, which enter the molecular layer and form a remarkably 

 rich arborization extending to the surface. The Golgi method shows 

 the larger and medium branches smooth, but the terminal branches 

 thickly beset with "gemmules." The dendritic arborization is 

 flattened, extending at right angles to the laminae. The axone is 



Fig. 347. — Purkinje Cell of Adult Human Cerebellum. Golgi preparation. (Cajal.) 

 a, Axone; b, recurrent collateral; d, spaces occupied by basket cells; c, spaces occupied by 

 blood-vessels. 



given off from the end opposite to the dendrites and passes through 

 the granular layer into* the white matter, either to one of the internal 

 cerebellar nuclei where it terminates, or to some other part of the 

 cortex. The Purkinje cells are almost the only cells the axones of 

 which enter the white matter. It is evident that all intracortical 

 connections must ultimately converge on these cells to reach the 

 eft'erent cerebellar paths. The axones of the Purkinje cells give off 

 collaterals not far from their origin, which pass into the molecular 

 layer and appear to terminate there in end "buttons" upon the 



