SUPPURA TION. 265 



capable of playing any pathologic role. The etiologic 

 relation of the organism to certain cases of purulent otitis 

 media in children was pointed out by Martha, Maggiora 

 and Gradenigo, Babes, Kossel, and others. H. C. Ernst 

 obtained it from a pericardial exudate during life. G. 

 Blumer demonstrated its presence in practically pure 

 cultures in a case of acute angina simulating diphtheria ; 

 Jadkewitsch, B. Motz, and Le Noir obtained the bacil- 

 lus in cases of urinary infection. The cases of Triboulet, 

 Karlinski, Oettinger, Ehlers, and Barker are interesting 

 instances of its role in cutaneous lesions. 



u In addition to these lesions, other morbid processes 

 have been associated in some cases with the bacillus of 

 blue pus, such as meningitis and bronchopneumonia by 

 Monnier ; diarrhea of infants by Neumann, Williams, 

 Theircelin and Lesage, and other observers ; dysen- 

 tery by Calmette and by Lartigau ; and general in- 

 fection by Ehlers, Neumann, Ottinger, Karlinski, Mon- 

 nier, Krannhals, Calmette, Finkelstein, and L. F. 

 Barker." 



It is interesting to observe, in passing, that this path- 

 ogeny can be set aside by the immunity which develops 

 after a few inoculations with sterilized cultures. These 

 are easily prepared, as the thermal death-point deter- 

 mined by Sternberg is 56 C. 



The bacillus appears to be rather common as a sapro- 

 phyte, and, as it has been found in the perspiration, 

 probably is not uncommon upon the skin. 



Before leaving the subject of suppuration attention 

 must be called to several rather common bacteria which 

 may at times be the cause of troublesome suppuration. 

 Among these are the pneumococcus of Frankel and 

 Weichselbaum, the typhoid bacillus, and the Bacillus 

 coli communis {q. v.). 



The fineumococcus has not infrequently been discov- 

 ered most unexpectedly in abscesses of the brain and 

 other deep-seated organs, and seems to have powerful 

 chemotactic powers. For a careful consideration of it 



