526 PATHOGENIC BACTERIA. 



disease; and that this bacillus ".r" is frequently found 

 in the intestinal contents of normal animals and of man, 

 as well as in the urine and the bronchial secretion. 



7. That, so far as your commission is aware, the 

 Bacillus icteroides has never been found in the body 

 other than of one infected with yellow fever ; and that 

 whatever may be the cultural similarities between this 

 and other micro-organisms, it is characterized by a spec- 

 ificity which is distinctive. 



8. That the Bacillus icteroides is very susceptible to 

 influences injurious to bacterial life and that its ready 

 control by the processes of disinfection, chemical and 

 mechanical, is assured. 



9. That the Bacillus icteroides produces in vitro as well 

 as in vita a toxin of the most marked potency, and that 

 from our present knowledge, there exists a reasonable 

 possibility of the ultimate production of an antiserum 

 more potent than that of Sanarelli. 



Archinard and Woodson and Archinard l found in 32 

 out of 39 autopsies a bacillus which quite accurately 

 corresponded with the Bacillus icteroides. Careful studies 

 of the agglutinating effects of the serum of yellow fever 

 and other febrile affections were made upon this bacillus 

 and the Bacillus icteroides, resulting in the observation 

 that in 80 per cent, of the cases the blood of yellow fever 

 cases or recent convalescents caused agglutinations of 

 both bacilli in dilutions of 1 : 40. The blood of typhoid 

 and dengue fevers does not cause the agglutinations ex- 

 cept in rare instances. 



Agramonte, 2 on the other hand, does not believe that 

 the specific germ of yellow fever is yet discovered. His 

 studies of Bacillus icteroides convince him that it is not 

 concerned in the etiology of the disease, as he failed to 

 find it in the blood of 16 out of 23 cases which he inves- 

 tigated, and declares that he found it in cases other than 

 yellow fever. 



1 A r . Y. Med. Journal, Jan. 28, 1899. 



1 Medical News, Feb. 10, 1900, vol. lxxvi., No. 6. 



