ANTIBACTERIAL SERA 57 



sealed in glass ampoules containing 1 and 2 c.c. each. 

 The appended chart (Fig. 3) shows the inoculations 

 and curve of opsonic indices illustrating the immunity 

 of the ram. 



From therapeutic employment of this antistaphy- 

 lococcic serum in many cases of carbuncles and fur- 

 uncles, in doses ranging from 1 to 6 c.c, the following 

 conclusions were drawn. 



1. The antistaphylococcic serum as herein pre- 

 pared and described possessed unquestionable thera- 

 peutic efficiency in a series of conditions, both general 

 and local, due to infections by the Micrococcus aureus, 



2. Biologic therapy by a potent polyvalent anti- 

 staphylococcic serum is more effective in the presence 

 of a staphylococcic bacterisemia than is the correspond- 

 ing autogenous bacterin. 



3. By virtue of the more immediate and decisive 

 effects of the antiserum, it deserves first choice over 

 the bacterin in the treatment of furunculosis and car- 

 bunculosis; on the other hand, a more intensive and 

 lasting immunity can be conferred on the individual 

 by supplementing the serum with two or three inocula- 

 tions of the autogenous bacterin. 



4. It is to be regretted that no attempt was made 

 to standardize this antiserum with respect to standard 

 units, since it must be conceded that the therapeutic 

 failure or inefficiency of many serums is referable to 



