150 APPLIED IMMUNOLOGY 



the serums of the cases tabulated in our series/ would 

 seem to justify the following assertions: 



1. A positive reaction is invariably reliable and al- 

 ways denotes the presence of a focus of gonococcic 

 infection. 



2. A negative reaction frequently occurs in the 

 presence of disease, especially in the acute and sub- 

 acute stages when the disease is limited to the urethra, 

 and it is always negative when the disease is confined 

 to the anterior urethra or vagina alone. 



3. In no alien non-gonorrhoeal infections of sys- 

 temic disease has a positive reaction been obtained ; the 

 test, therefore, appears to be absolutely specific. 



4. A positive reaction has been found to be present 

 in 21.05 per cent, of patients clinically cured. Such 

 patients, therefore, should not be discharged from 

 treatment or observation until a negative reaction has 

 been obtained. 



5. Not infrequently, either when suspicious lesions 

 are presented or accidentally, positive reactions will be 

 discovered in patients denying gonorrhoea. 



6. In only 9.09 per cent, of cases of acute and sub- 

 acute antero-posterior urethritis has the complement- 

 fixation test resulted positively. The earliest ap- 

 pearance of a positive reaction in a primary attack of 



^ Archiv. Int. Med., January, 1914, p. 143. 



