208 APPLIED IMMUNOLOGY 



The forms of genito-urinary tuberculosis amenable 

 to tuberculin include hacillary tuberculous nephritis, 

 where both kidneys are functionally sufficient, but the 

 primary or more affected kidney is indeterminable; 

 bilateral, functionally insufficient, hence inoperable 

 tuberculous kidneys; secondary ureteritis and cystitis 

 following nephrectomy for tuberculosis and primary 

 or secondary epididymitis, prostatitis, seminal vesiculi- 

 tis and salpingitis. Exact discrimination must be 

 exercised in the latter conditions as to whether the 

 tuberculin syringe shall precede or follow the scalpel. 



Perhaps the best results in tuberculin immuniza- 

 tion have occurred in the treatment of chronic osteitis 

 and arthritis. Frequently there is a superimposed 

 mixed infection in these cases, calling for the pre- 

 liminary or alternative employment of autogenous 

 bacterins ; repeated cultures become necessary at least 

 biweekly, to identify the changeable pyogenic bacteria 

 for preparation of the correct bacterin. We have 

 treated many such cases of knee, spinal, and hip- joint 

 disease with excellent results (Fig. 19). In acute 

 osteomyelitis and arthritis, tuberculin therapy should 

 be condemned. 



Intestinal and peritoneal tuberculosis offers little 

 promise for tuberculin. We have experienced re- 

 markable results using tuberculin following explora- 

 tory laparotomy revealing extensive nodular tuber- 



