238 



APPLIED IMMUNOLOGY 



count of a prolonged " negative phase," or possibly 

 the establislmient of immunity and recovery. Failure 



Fig. 33. — Case of gonorrhceal arthritis of knee, sho-wing manner of differentiation 

 between the possible causes of synovitis or arthritis. The opsonic indices for the two 

 suspected etiological organisms were determined before the application of passive hy- 

 peraemia to the infected joint. After intermittent application for one and a half hours 

 the indices were again taken, with the result that the opsonic index for the gonococcus, 

 the specific organism in this case, had risen considerably. 



to evoke a rise in the opsonic index may be attribut- 

 able to (1) too small dosage, (2) reinoculations dur- 

 ing the negative phase, or (3) inoculation treatment 



