BACTERIAL INOCULATION 



245 



Spontaneous auto-inoculation is frequently observed 

 in a patient the victim of subacute or chronic phthisis 

 pulmonalis, and is characterized by the irregular flares 

 of temperature. If the doses of bacteria or their prod- 

 ucts, which at these times are cast off into the general 

 circulation, are too great or repeated too often, the pa- 



11 



i 



5 



I 



s 



16- 



I 



si 



11 



^ 



Fig. 36. — Case of gonococcal arthritis. Showing the effect of massage on the gono- 

 cocco-opsonic index. I =inoculation of 30,000,000 gonococci. M =massage. (Dr. 

 J. Freeman.) 



tient is thrust into a profound or permanent " nega- 

 tive phase " and death supervenes. If, on the other 

 hand, the dose of re-infection be of the proper size 

 and occurs opportunely, the patient becomes to a cer- 

 tain extent immunized and at least a temporary re- 

 covery takes place. Induced or artificial auto-inocula- 

 tion is a most interesting problem and at times has 



