BACTERL4L INOCULATION 



251 



ately or acutely ill patients, or with patients in whom 

 a beneficial response has been obtained with the mini- 

 mal effective dose, this should not be exceeded. With 

 chronic cases, presenting well-localized lesions, the 

 average or maximal dose may be administered at the 

 start, and subsequently increased. The following 

 table, giving the minimal, average and maximal doses 

 employed in the authors' experience, may prove of 

 service : 



THERAPEUTIC DOSE TABLE 



Bacterin 



Gonococcus 



Colon 



M. Catarrhalis 



Influenza 



Typhoid 



Pneumococcus 



Streptococcus 



Staphylococcus 



B. Punctatum 



B. Proteus Vulgaris. . . 



B. Friedlander 



B. Acnes 



Pertussis 



Diphtheria 



Pseudodiphtheria .... 



B. Pyocyaneus 



B. Fluorescens 



B. Pseudotuberculosis 



Rodentium 



B. Acidi Lactici 



B. Lactis Aerogenes. . . 



B. Mallei... 



B. Fusiformis 



B. Koch- Weeks 



B. Morax-Axenfeld . . . , 

 Tuberculin 



Actinomycotin . 



Minimal effective dose 



Average dose 



2 to 

 5 to 



10 to 

 5 to 

 5 to 



10 to 

 2 to 



50 to 



10 to 

 5 to 



10 to 

 5 to 

 5 to 

 5 to 



10 to 



5 million 

 10 million 

 25 million 

 10 million 

 10 million 

 20 million 

 5 milHon 

 100 million 

 25 million 

 10 million 

 20 million 

 10 million 

 10 million 

 10 million 

 25 million 



25 million 



2 to 

 10 to 



5 million 

 25 million 



0.00001 to 0.0001 



milligram 

 0.001 milligram 



50 to 

 25 to 

 50 to 

 25 to 

 25 to 

 25 to 

 25 to 

 100 to 

 100 to 

 50 to 

 50 to 

 25 to 

 25 to 

 25 to 

 50 to 

 50 to 

 50 to 



100 million 



50 million 



100 million 



50 million 



50 million 



50 million 



50 million 



400 million 



200 million 



100 million 



75 million 



100 million 



100 million 



50 million 



100 million 



100 million 



100 million 



Maximum dose 



50 to 100 million 

 50 to 100 million 

 50 to 100 million 



50 to 100 million 

 50 to 100 million 

 50 to 100 million 

 0.0001 to 0.001 



milligram 

 0.01 to 0.1 milli- 

 gram 



400 million 

 400 million 

 300 million 

 200 million 

 500 million 

 300 milHon 

 200 million 

 1000 million 

 400 million 

 400 million 

 300 million 

 200 million 

 200 million 

 100 million 

 300 million 

 400 million 

 400 million 



400 million 

 400 million 

 400 million 



400 million 



400 million 



250 million 



100 milligrams 



4 milligrams 



