BACTERIAL INOCULATION 277 



preparation in quantities of 0.05 to 0.5 c.c. produces a 

 reaction which is invariably constant in gonorrhoeal 

 subjects. A rise of temperature above 1.5° C. after 

 an injection, of 1 c.c. may be regarded as pathogno- 

 monic. Therapeutically, with increasing dosage, the re- 

 sults have been no better than with the subcutaneous 

 administration of bacterins or sero-bacterins, and it is 

 extremely doubtful if intravenous injection will super- 

 sede the older method, properly interpreted, in a diag- 

 nostic capacity. 



Prostatitis and Seminal Vesiculitis, — The writers 

 believe that these complications, in addition to the 

 gonococcus, are commonly precipitated and perpetu- 

 ated by a mixed infection due to the Streptococcus, 

 PneumococcuSj Colon bacillus, M, catarrhalis, etc. 

 They have obtained in many instances gratifying re- 

 sults by alternating a decivalent gonococcus stock and 

 autogenous bacterins, the latter prepared from urine 

 cultures after massage of prostate and seminal vesi- 

 cles, when, in addition to the above, other organisms, 

 as the Micrococcus alhus, aureus, citreus, candicans, 

 Candidas and orbicularis, the Bacillus typhosus, pyo- 

 cyaneus and acidi lactici and the Cory neb acterium 

 pseudodiphtheriticum, have been isolated. The 

 therapy has been conducted only in the subacute and 

 chronic cases, preferably in the presence of suppura- 

 tive inflammations ( Fig. 52 ) . 



