BACTERIAL INOCULATION 



281 



from the os calcis (osteophytes, exostoses) the ad- 

 ministration of gonococcus bacterin has rendered 

 operative intervention unnecessary, or at least has 

 eliminated toxins and insured a more satisfactory 

 post-operative result. In chronic cases it is even more 



Fig. 54. — Sam. S. Acute osteomyelitis of tibia followed by septictemia. The 

 arrow indicated when a blood culture demonstrated M. aureus; the crosses represent 

 the times of inoculations with M. aureus bacterin. Observe that the patient, as indi- 

 cated by the increased fluctuations of temperature, progressively grew more septic, 

 and that bacterin therapy was not only useless, but possibly harmful. The substitution 

 of bacterin at the juncture by antistaphylococcic serum apparently exerted a definite 

 beneficial influence for recovery. 



meritorious, if caries and sequestra are excluded and 

 hypergemia used to augment the treatment. In our 

 experience bacterins and tuberculins have done more 

 harm than good in acute osteomyelitis (Fig. 54). 



Synovitis and Arthritis, — Associated with these 

 diseases the Streptococcus rheumaticus, Gonococcus, 



