BACTERIAL INOCULATION 



287 



as determined by the Schick reaction (see p. 191) , are 

 eliminated, the results of active immunization, em- 

 ploying either autolyzed diphtheria bacilli themselves 

 or toxin-antitoxin mixtures, have not been brilliant 

 and do not by any means warrant its substitution for 



Fig. 56. — Cultures both from ethmoidal sinuses and bronchial expectoration dem- 

 onstrated the Streptococcus pyogenes in preponderance, together with the pneumococcus, 

 staphylococcus and M. catarrhalis. _ Opsonic indices were taken only for the strepto- 

 coccus, although therapy waa carried out by inoculations with the autogenous mixed 

 bacterin. 



antitoxin. In the first place, the formation of pro- 

 tective antibodies is slow, seldom before the second 

 week, hence the superiority of immune serum in epi- 

 demics, both prophylactically and therapeutically. 

 Park and Zingher point out that there is lack of a 

 sufficient response to active immunization in at least 



