mi: n ACILI.I s OK \\ INK \ \ 1\". 



lured MS a result of the distent inn, and tin* haeilli, tovvl her \\illi 

 escaped hlood corpuscles, will ho seen ill the surround in:-, ti n- In 



llio kidneys tho i;-|oincmli, especially, appear MS if iujoctod \\illt -o| 

 'ivd threads, and hy rupture lliese may lind Iheir \\ a \ ml.. I he inini 

 ferous tuhulos. 



These appearances Mild the tfoiioml symptoms indicate- Mi.,1 llio 

 disease produced hy (he introduction of this haeillu in!<> (lie hndie-i <>l 

 suseeplihle animals is a . ^ouuino H(pl ioa'MUM. AM in olhor I'onn-* of 

 HO])li< g M'inia ; 1 he spleen is ft mi id l > he ;, i .il I \ nl n . <! ; M has a dark 

 e.|oi- and is sofl and I'riahle. \\'ilh tin exception theorem pie 

 KOI 1 1 no not;ihlo olia 1 1 < all IK >uj;'li I h< h \ er is a pi I < > he sol now lull 

 enlarged. In llio guinea piv; an exteir i\e i nllanillUil< n \ <edi m.i. e\ 

 lei id in:'; In >m 1 he point of inocilhtt ion l< I I n m. . I d(>pendoiil pa i I ! 

 the hodv, is developed ; (he snhenlanei.iis e .niieel i \'< ti ne i mlil 

 Iraled will) hloi idy serum an<l IIMM u }vla 1 1 IIOIIM upptMi ranee Tin 

 animal comes IM-.X! hi Hie IIH.IISC ill HUHCopI ihihl \ . and culliires \vhhh 



IK', liwlllir ink Mir,. 



atlennated t ex lent t halt hey will not, kill a rahhit oj a 



-heep may still kill ag'in n< a pi# ; or, if not. may I-. ill ;i moilHO. PaHfenr 

 haB nhown that the pathogenic power of the h;willuH may h < iah 

 linh^d hy inoculations into n < -ephhle animals, and that an allenn 

 at<-(| cult un; whicli will not kill an adult guinea pi;' ma;, h< fatal lo 

 ery yf^UJJl/ UnJJIia,! of thlhi Kpeeje:^ a nd that culture'-' I roll) the hlood 

 of tlliH will li;i . in'Tea-e*| palh'/rM-uir- vii ule f) r , . 



\''-ry ruiuutf' fjUantiti< <>\ . nt ' -uh n nfalhhl , lalal to 



r/jo ^ 'i '-f;ptihl<} aniinalH, hut for ral>hitH and other |< : 

 cr-j/tihhj BIiirnalH th(i <juantity injeeier) inlluefjee;, t),( r-e:-ull, and M 



