520 BACILLI WHICH PRODUCE SEPTICAEMIA 



vomiting, or efforts to vomit. Death usually occurs at the end of two or 

 three days. At the autopsy the spleen is found to be normal, the other or- 

 gans slightly hyperaamic, and the intestinal mucous membrane in a state of 

 catarrhal inflammation. The bacilli are found in the blood and in the vari- 

 ous organs in considerable numbers. 



PROTEUS CAPSULATUS SEPTICUS. 



Obtained by Banti (1888) from a case of " acute haemorrhagic infection." 

 According to Banti, this is possibly identical with the preceding species 



Proteus hominis capsulatus but in some respects more nearly resembles 



Friedlander's bacillus. 



BACILLUS ENTERITIDIS. 



Obtained by Gartner (1888) from the tissues of a cow which was killed in 

 consequence of an attack characterized by a mucous diarrhosa, and also from 

 the spleen of a man who died twelve hours after eating the flesh of this 

 animal. 



Morphology. Short bacilli, about twice as long as broad, frequently united 

 in pairs; chains of four to six elements are sometimes seen. 



Stains with the usual aniline colors, and presents the peculiarity of 

 staining deeply at one end while the remainder of the rod is but slightly 

 stained. When two bacilli are united the deeply stained ends are in apposi- 

 tion. 



Biological Characters. An aerobic, non-liquefying, motile bacillus. 

 Spore formation not determined. Grows in the usual culture media at the 

 room temperature. Upon gelatin plates pale-gray, superficial colonies are 

 formed at the end of twenty-four hours; under a low power these are seen 

 to be coarsely granular and transparent ; the central portion usually pre- 

 sents a greenish color ; deep colonies are spherical, indistinctly granular, 

 and of a brownish color ; in older colonies a marginal transparent zone is 

 seen which appears to be made up of minute fragments of glass of a pale- 

 brown color. In gelatin stab cultures but slight development occurs along 

 the line of puncture ; upon the surface a thick, grayish- white layer is 

 formed, which after a time becomes very much wrinkled. Upon the surface 

 of agar, at 37 C., at the end of eighteen to twenty hours a grayish- yellow 

 layer has formed. Upon potato a moist, shining, yellowish-gray layer is 

 developed. The growth upon blood serum is rapid in the form of a gray 

 layer along the line of inoculation. 



Pathogenesis. White mice and house mice usually die in from one to 

 three days when fed with a pure culture of this bacillus. Babbits and gui- 

 nea-pigs die in from two to five days from subcutaneous injections less 

 pathogenic for pigeons and canary birds. Dogs, cats, chickens, and sparrows 

 are immune. A. goat died in twenty hours after receiving an intravenous 

 injection of two cubic centimetres of a culture in blood serum. The princi- 

 pal pathological appearance consists in an intense inflammation of the in- 

 testinal mucous membrane. The bacilli are found in blood from the heart 

 and also in the contents of the stomach. 



BACILLUS OF GROUSE DISEASE. 



Obtained by Klein (1889) from the lungs and liver of grouse which had 

 succumbed to an epidemic disease. 



Morphology. Bacilli with rounded ends, from 0.8 to 1.6/^long; may 

 also be seen as spherical or oval cells 0.6 /j. long and 0.4 jn thick; solitary, in 

 pairs, or in chains of three to four elements. 



Stains best with Weigert's solution of methylene blue in aniline water. 



Biological Characters. An aerobic, non-liquefying, non-motile bacillus. 

 Spore formation not observed. Grows in the usual culture media at the 



