G02 



PATHOGENIC SPIRILLA. 



during the attack these spirilla are found in increased numbers be- 

 cause conditions are more favorable for their development, but that 

 they have no etiological import. The writer would remark that, in 

 very extended researches made in the United States and in Cuba, he 

 has never found any microorganism resembling Koch's cholera spi- 

 rillum in the faeces of patients with yellow fever or of healthy indi- 

 viduals, or in the intestinal contents of yellow-fever cadavers. 



SPIRILLUM OF FINKLER AND PRIOR. 



Synonym. Vibrio proteus. - 



Obtained by Finkler and Prior (1884) from the faeces of patients with 

 cholera nostras, after allowing the dejecta to stand for some days. Subse- 



Fio. 180. 



FIG. 181. 



FIG. 182. 



X 1,000. From a photomicro- 



FIG. 180. Spirillum of Finkler and Prior, from a gelatin culture, 

 graph. (Frankel and Pfeiffer.) 



Fia. 181. Spirillum of Finkler an! Prior; colonies upon gelatin plate; a, end of sixteen hours; 

 6, end of twenty-four hours; c, end of thirty-six hours, x 80. (Fliigge ) 



FIG. 182. Spirillum of Finkler and Prior; culture in nutrient gelatin; c, two days old; d, four 

 days old. (Flugge.) 



quent researches have not sustained the view that this spirillum is the speci- 

 fic cause of cholera morbus. 



Morphology. Resembles the spirillum of Asiatic cholera, but the curved 

 segments (" bacilli") are somewhat longer and thicker and not so uniform 

 in diameter, the central portion being usually thicker than the somewhat 

 pointed ends; forms spiral filaments, which are not as numerous, and are 

 usually shorter than those formed by the cholera spirillum. In unfavorable 

 media involution forms are common large oval, spherical, or spindle- 

 shaped cells, etc. Has a single flagellum at one end of the curved segments, 

 which is from one to one and one-half times as long as these. 



Stains with the usual aniline colors best with an aqueous solution of 

 fucbsin. 



