THE DESTRUCTION OF BACTERIA 93 



prepared a number of different organic chlorin compounds which 

 were soluble in oil, and which yielded up the chlorin rather slowly 

 to the wound secretions, so that the action continued over a com- 

 paratively long time. Chloramine T (1) and Dichloramine T are 

 the two most practicable compounds ; these substances have the fol- 

 lowing formulae : 



CH 3 



SO 2 NaNCl SO 2 NC1 2 



Chloramine-T Dichloramine-T 



They contain chlorin replacing hydrogen in an amino group, and 

 this chlorin is liberated slowly, in contact with protein material. 

 They are used in solution in oil, either chlorinated paraffin oil or oil 

 of eucalyptol, and are applied as a spray or on gauze. 



Eusol. The simple neutralization of calcium hypochlorite with 

 boric acid renders it comparatively non-irritating, and under the 

 name of eusol (2) this solution has been widely used. 



For original articles on the use of Dakin 's Solution, see below: 37 



TERCHLORIDE OF IODIN (IC1 3 ) is an extremely strong disinfectant, 

 being efficient for vegetative forms in solutions of 0.1 per cent in 

 one minute and a 1 per cent solution destroying spores within a few 

 minutes. 38 



Painting with TINCTURE OF IODIN (10 per cent) is a simple and 

 reliable method of sterilizing the skin. It is now used in many 

 clinics in sterilizing the field of operation. 



IODOFORM (CHI 3 ) 39 is weakly antiseptic in itself, but when in- 

 troduced into wounds where active reducing processes are taking 

 place often as the result of bacterial growth iodine is liberated 

 from it and active bactericidal action results. 



PEROXIDE OF HYDROGEN is formed by the action of dilute sulphuric 



87 Dakin, Brit. Med. Jour., August 28th, 1915. Carrel, Dakin, Daufresne, 

 Dehelly and Dumas, Presse Medicale, October llth, 1915. Dakin and Dun- 

 ham, " Handbook of Antiseptics," New York, 1917. Lorrain Smith, Dren- 

 nan, Eettie and Campbell, British Med. Jour., July 24th, 1915. See also Carrel 

 and Dehelly, "Infected Wounds," Hoeber, N. Y. 1919. 



3s Behring, Zeit. f. Hyg., ix, 1891. 



39 v. Behring, < < Bekaempf ung d. Inf ektions-Krankh., " Leipzig, 1894. 



