STAPHYLOC :<>((' I IS I'YO( !! INKS AURKIIS 



of leucocyte extracts in animals infected with Staphylococcus 

 pyogenes aureus lias given encouragement for such treatment in 

 human beings. A number of staphylococcus infections in man have, 

 been successfully treated with leucocyte extracts by Hiss and 

 Zinsser. 



Passive immunization with anti-staphylococcus sera has not been 

 a therapeutic success. Kx tensive work has been done especially 

 by German investigators in animal experimentation, but in most 

 cases it lias been found that serum injections were of little use if 

 administered after the. infection had been established. Injection 

 into the test animals before infection or at the same time with 

 infection sometimes gave favorable results. In man, passive im- 

 munization has not been encouraging, although we believe that hope 

 of some benefit in this direction should not be completely abandoned 

 until the antigcnie classification of the staphylocoeci has been 

 attempted. 



Hooker 4 " has recently reported a number of cases in which he 

 lias transfused into patients suffering from staphylococcus scp- 

 ticemia the blood of donors irnmuni/ed with staphylococcus vaccines. 

 This procedure of course would be applicable only to subacute cases, 

 but in the procedure of Hooker there seems to be promise. 



STAPHYLOCOCCUS PYOOKNKB ALDUS. This coccus differs from 

 Staphylococeus pyogenes aun-us simply in the absence of the golden 

 yellow coloration of its cultures. Morphologically, culturally, and 

 pathogenically, it is in every way identical with the staphylococcus 

 described in the preceding section, but its toxin- and enzyme-produc- 

 ing powers in general are less developed than those of the aureus 

 variety. Its close biological relationship to aureus is furthermore 

 demonstrated by its agglutination in Staphylocoeeus pyogenes aureus 

 immune sera. 



ST.M'jjyi.oc'"-' Dfi KPIDKKMIDIS ALBTS. The Staphylococcus epi- 

 dermidis albus described by Welch is merely one of the rion- 

 mthogemc varieties of Staphylococcus pyogenes albus and possibly 

 loes not deserve separate classification. It may give rise to unim- 

 portant abscesses. 



ST.\KFJYJ.or<r CUfi PYDOENHE On BEO& Staphylococcus pyog<-n-s 

 'it IT-US produces a bright yejlow or lemon-colored pigment of dis- 

 tinctly different hue from that of Staphyloeoeeus pyogenes aureus. 



" Hooker, An. of Surgery, Nov., 1917, p. 51.'i. 



