862 



PATHOGENIC MICROORGANISMS 



Norris, Pappenheimer, and Flournoy, 41 in smears stained by poly- 

 chrome methods, have described long, filamentous tapering ends 

 which they interpreted as bipolar, terminal flagella, never observing 

 more than one at each end. Spores are not found. 



Cultivation. Innumerable attempts to induce these microorgan- 

 isms to multiply upon artificial media have been made. Novy and 



FIG. 93. SPIROCILETE OF RELAPSING FEVER. (After Norris. Pappenheimer, and 



Flournoy.) 



Knapp succeeded in keeping the microorganisms alive and virulent 

 in the original blood for as long as forty days, and call attention 

 to the fact that the length of time for which they may be kept alive 

 depends to a great extent upon the stage of fever at which the 

 blood is removed from the patient. They do not, however, believe 

 that extensive multiplication, or, in other words, actual cultivation, 

 had taken place in their experiments. Norris, Pappenheimer, and 

 Flournoy, on the other hand, have obtained positive evidence of 



"Norris, Pappenheimer , and Flournoy, Joiir. of Inf. Dis., 3, 1906. 



