1096 PATHOGENIC PROTOZOA 



Animal Pathogenicity. The disease occurs naturally in African 

 dogs, and they are probably the source of infection, the parasite being 

 carried by a flea or some other insect. Dogs, monkeys and guinea-pigs 

 are susceptible to artificial inoculation. 



Treatment. The use of tartar emetic in the treatment of kala-azar 

 is due to the success of the treatment of infantile leishmaniasis intro- 

 duced by Di Christina and Caronia. In kala-azar it has now been 



L r* -.>*' J 



FIG. 145. LEISHMANIA INFANTUM. (Army Med. School Collection, Washington, 



B.C.) 



used successfully by many and when properly given is without danger 

 and gives a large number of recoveries. 



The untreated disease has a mortality of about 90%. Dobbs- 

 Price 11 has reported 2000 injections with 67% of recoveries. He used 

 a 1%% solution of sodium antimony tartrate, in a weekly dosage 

 increasing from 1 to 8 c.c. 



11 Dodds-Price, J., Kala-Azar in Europeans in the Nowgong District of Assam 

 Indian Medical Gazette, 1920, Vol. 55, No. 3, pp. 87-89. 



