398 



THE DIGESTIVE SYSTEM 



With the increased breadth of the basal zone during se/eretion, there 

 appears in this portion of the cell a structure which /has been de- 

 scribed by Nussbaum (Arch. mikr. Anat., 1885) fa iiie Nebenkern, 

 and which has been carefully studied by Mathews (Jour, of Morph., 

 1899). This is a spheroidal basophil body which lies near the nucleus 

 and is frequently surrounded by a clear area of cytoplasm. Its origin 



and function are undetermined 

 and it is possible that several 

 distinct bodies have been in- 

 cluded under the name. Ogata 

 (Arch. f. Phyaiol., 1883) con- 

 siders that it is derived from 

 the nucleus by the extrusion 

 of its plasmos6me, an opinion 

 which seems to be shared by von 

 Ebner (Kolliker's Handbuch, 

 1902, Bd. iii, 5, 250). The 

 studies of Mathews have shown 

 that at least in certain instances 

 ACINUS OF CAT {i is distinctly fibrillar and sug- 

 NEAR FUNDUS, gest that it may\ be concerned 

 with the mechanism of secre- 

 tion. It most 'probably repre- 



The alveoli of the central portions of , 



the cells represent Hissnl/ *vmopn sents a post-secret\on remnant 

 granules. X 1500. 



FIG. 370. PANCREATIC 

 CUT TRANSVERSELY 

 SHOWING THE BASAL (PROZYMOGEN) 

 FILAMENTS OF THE CELLS. 



centra 



dissolved zymogen 



% 



of ergastopljasmic Vbasal fila- 

 ments. 



In addition to this fibrillar complex of basophilous substance, there 

 may be seen in appropriately fixed and stained preparations,, another 

 group of fibrils, the mitochondria. These can be seen in fresh acinar 

 cells and in tissue preserved in fluids which lack acidjS (mitochondria are 



dissolved by acids), when they also give to the ba 

 cells a striated appearance. These basal bodies h* 

 studied by Bensley (Amer. Jour. Anat., 12, 3, 1911 

 the guinea pig, and their independence from the 

 Solger established. Mislawsky also (Arch. mikr. . 



al portion of these 

 Ve been extensively 

 in the pancreas of 

 basal filaments of 

 inat., 81, 4, 1913) 



has recently studied the mitochondria in the acinar qells of the rabbit's 

 pancreas. He finds no evidence to indicate that they segment into the 

 zymogenic granules. They are described as interstitial elements of the 

 protoplasmic reticulum, more probably connected with the general cell 

 metabolism. There is apparently no good evidence in support of the 



