782 DIRECTIONS FOR LABORATORY WORK 



(E) PERIPHERAL NERVE TERMINATIONS (END-ORGANS). 



(a) Nerve Endings in Epithelium. (1) Sketch (133) a bundle of 

 naked nerve end-fibrils in a demonstration slide of thick skin or cornea, 

 stained by the intravitain methylene-blue method. In the same prepara- 

 tion search for tactile cells of Merkel. Note tactile meniscus at end of 

 nerve fibril and the associated tactile cell. Sketch (134). 



(2) Sketch (135) a taste bud from a circumvallate papilla of the 

 human tongue or a foliate papilla of the tongue of the rabbit, in stained 

 section. Note the gustatory cells, the sustentacular cells and the basal 

 cells; and in specially stained preparation note also the nerve fibrils 

 terminating in relation to the cells of the taste bud. 



(b) Nerve Endings in Connective Tissue. (1) Study a stained sec- 

 tion of skin of finger tip. Distinguish between vascular and tactile 

 papillae of the derma, Sketch (136) a tactile corpuscle (of Meissner) 

 from a tactile papilla. 



(2) Sketch (137) a lamellar (Pacinian) corpuscle from a stained 

 toto mount of a fragment of the cat's mesentery. Sketch (138) a sim- 

 ilar corpuscle in section in the interlobular connective tissue, from a 

 stained section of the pancreas. Sketch: (a) a corpuscle of Herbst 

 (139) ; (b) a corpuscle of Grandry (140), from a stained section of 

 duck's bill. 



(c) Nerve Endings in Striped Muscle and in Tendon. (1) sensory; 

 muscle spindles and tendon spindles. 



.(2) motor; motor end-plates in muscle. 



Study and sketch (141) from special demonstration slides. What is 

 the character of the sole plate? relation -to 'intermediate' or 'receptor' 

 substance of myoneural junction? function of the different nerve end- 

 organs ? ( Consult following scheme of classification, arranged in accord- 

 ance with the terminology proposed by Sherrington.) 



