TABLE OF CONTENTS 



PAGES 



I. Historical review 1-10 



II. Feeding and implantation experiments with white rats 11-64 



Methods 11-13 



Preliminary feeding experiments 18—16 



Carbohydrate feeding 17-21 



Administration of living suspensions of Bacillus acid- 

 ophilus 21-34 



Bacillus acidophilus and carbohydrate feeding . . . 34—49 



Bacillus acidophilus versus Bacillus bulgaricus feeding . 49-52 

 Slow carbohydrate absorption in the intestine and its 



relation to Bacillus acidophilus implantation . . . 62-61 

 Relation of hydrogen ion concentration to the character 



of the intestinal flora > 61—63 



Conclusions 63-64 



III. Feeding and implantation experiments with human 



subjects 65-110 



The basal daily diet 66-69 



Carbohydrate feeding 70 



Transforming influence of lactose 70 



Transforming influence of dextrin 70-77 



Implantation experiments with living cultures of Bacillus 



acidophilus 78-79 



Simultaneous use of the special carbohydrates and Bacil- 

 lus acidophilus 79-84 



Transforming influence of milk cultures of Bacillus acid- 

 ophilus on the intestinal flora 85-94 



The use of Bacillus acidophilus milk reinforced with lac- 

 tose or dextrin 94-99 



Attempts to implant Bacillus bulgaricus in man . . . 99-106 



Incomplete absorption of lactose from the intestine . . 106-107 

 Relation of hydrogen ion concentration to the character 



of the intestinal flora 108-110 



IV. A full account of the preparation of Bacillus acid- 



ophilus milk for human consumption, and of its 



known properties 111-113 



V. Methods employed in the routine examination of feces 114-117 



The use of whey agar plates 114-116 



Veillon tubes 116-116 



Direct microscopic examination of fecal suspensions . 117 



VI. General discussion and summary 118-124 



Explanation of plates 126-126 



Bibliography 127-136 



