EXPERIMENTS WITH HUMAN SUBJECTS 99 



TABLE 64— SUBJECT R 



Ordinary Daily Diet + B. Acidophilus Milk 500 cc. Lactose 100 oms. 



ATTEMPTS TO IMPLANT BACILLUS BULGARICUS IN MAN 



In the two following experiments B. bulgaricus was administered in 

 the form of milk cultures which were prepared with the same strains 

 that were employed in previous experiments on white rats. The method 

 of preparing these sour milk cultures of B. bidgaricus was identical with 

 the procedure followed for the B. acidophilus milk. 



Two subjects were chosen who had been particularly susceptible to 

 the administration of B. acidophilus milk, 500 cubic centimeters of this 

 product being sufficient to bring about a very profound change in the 

 intestinal flora. The B. bulgaricus feeding was continued for ten days, 

 and the daily amount consumed was 1000 cubic centimeters, taken twice 

 a day between meals in 500 cubic centimeter portions. This was imme- 

 diately followed by a five day period in which the subjects were given 

 neither B. bulgaricus, B. acidophilus nor special carbohydrates. Fol- 

 lowing this control period, milk cultures of B. acidophilus were admin- 

 istered to the same two individuals, but instead of 1000 cubic centi- 

 meters being used, only 500 cubic centimeters were consumed daily. 



