ADDENDUM 5 I 



ficcl as to produce peculiar if not defective individuals when measured by the 

 standard of the average. 



"With this conception we may find some physiological or pathological 

 basis for what is regarded by many as a psychotherapeutic phantasy; for 

 the various neuroses and asthenias may arise primarily as the result of some 

 disturbance of internal secretion which proves the way for the dreams, 

 symbolisms, neurograms and other acrostical manifestations dissected by 

 the psychoanalyst. If therefore we are to swallow the Freudian doctrines 

 whole a difficult morsel for many and are to interpret hysteria and the 

 psychoneuroses solely as the resultant of early mental conflicts and com- 

 promises between the libido and its repressions, it will be easily seen that any 

 secretory duration which on the one hand excites, or on the other diminishes, 

 sexual activities must be an important element in modifying the terms 

 affecting the ultimate compromise. 



"We have of course been considering extreme examples, but is quite 

 probable that the psychopathology of everyday life hinges largely upon 

 the effect of ductless gland discharges upon the nervous system. This is 

 particularly worthy of consideration in the study of child psychology^ in 

 its relation to puberty and adolescence, especially in those individuals in 

 whom there is some underlying, possibly inherited, functional deviation in 

 the chemistry of the internal secretion. At any age, however, in the pres- 

 ence of some ductless gland irregularity, which in chemically speaking more 

 stable individuals would be transient, may produce secretory disturbances, 

 characterized by more or less chronicity." 



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"It is hoped that some serological test, possibly in the direction of 

 Abderhalden's investigations on the serodiagnosis of pregnancy, will serve 

 to give as a chemical reaction of diagnostic value, at least, for states of over- 

 activity of individual glands . . . and we possibly may come to attach an im- 

 portance to the findings of pathological serology far greater than that which in 

 the past we have given to the cytological changes shown in the microscope. " 



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It was part of the philosophy of the ancients to explain change in matter 

 as due to the "love" of the elements. We still speak of chemical affinities. 

 Nowadays we resolve love into its chemical constituents. All of which 

 makes not one whit less, but rather much more wonderful, the phenomena 

 manifested by the various bindings together of atoms. 



Thus is the Freudian theory placed on a materialistic basis with re- 

 gard to the genesis of certain of the epiphenomena of some of the neuroses. 

 That the underlying factor of heredity governs here the constitution, pre- 

 disposing either the ductless glandular or the nervous factor or both to ab- 

 normal action, there can be no doubt. One thing at least we may be assured 

 of: without internal secretion, no thoughts. The fact, however, that the 

 nervous tissue seems to be especially susceptible to the influence of the 



