HYPOPHYSIAL DYSTROPHY 297 



statement there exists a certain amount of libido and vita sexualis, and he believes that 

 he would have potentia coeundi. He states, however, that nightly pollutions almost never 

 occur. 



About 170 cm. tall, the skin quite soft, mustache and beard are almost completely ab- 

 sent, axillae show but very sparse hairiness, on the mons Veneris rather good, closing off 

 above in a horizontal line, otherwise hairiness of the trunk and extremities is entirely 

 absent. 



Typical eunuchoid fat deposits. Mammae extremely rich in fat, as are also the vicin- 

 ity of the hip, and the mons Veneris. The small penis is embedded in a cushion of fat. 

 Testicles of rather normal size and consistency. Genu valgum on each side. 

 Alimentary glycosuria (100 gm. dextrose), negative. 

 Blood count: Erythrocytes, 4,240,000 

 Hemoglobin (Sahli), 65 per cent. 

 Leucocytes, 6500, of which: 

 Neutrophiles, 65 per cent. 

 Mononuclears, 28 per cent. 

 Eosinophiles, 7 per cent. 



X-ray examination of the skull shows normal relations. 



On freely chosen administration of liquid, an average of 7400 cc. of urine per day. 

 The investigation as to the specific gravity of the urine at different times of the day shows 



6-1 1 A.M. 1550 cc. 1008 



11-4 P.M. 1300 cc. 1008 



4-9 P.M. 1900 cc. 1004 



9-6 A.M. 1600 CC. IOO2 



After addition of 15 gm. of common salt to the breakfast 



6-1 1 A.M. 1200 cc. 1007 



11-4 P.M. 1850 cc. 106*7 



4-9 P.M. 1950 CC. 1007 



J9~6 A.M. 2600 cc. 1004 



Summary. Combination of eunuchoid obesity and deficient development of the 

 condary sexual characters with diabetes insipidus. Growth-disturbance is absent, as is 

 so any disturbance worth while in the ossification. Probably disease of the brain-stem 

 unknown nature. 



a. Frankl-Hochwart emphasizes that in tumors of the hypophysis without 

 acromegaly, often the temperature is established at subnormal values; he 

 himself observed this in three of ten cases. In the case of Gotzl-Erdheim the 

 temperature varied between 35 and 36, only exceptionally rising as high 

 as 36.3. Among my cases this was very evident in case Si, Observation 

 XXXIV, here the temperature varied for a time between 36 and 36.6; 

 and in case F, Observation XLIV (see later), the temperature varied for a 

 while between 36 and 36.4; and later even between 35.8 and 36.2. We 

 could bring this reduction of body temperature into relation with the 

 reduction of the metabolism, as is the case in myxedema. Everything 

 speaks for the point of view that also in hypophysial dystrophy the vegeta- 

 tive functions proceed slower than in normal individuals. 



It seems, however, almost as though in hypophysial dystrophy the regu- 



