328 THE DISEASES OF THE HYPOPHYSIS 



resulting from the breaking down in the pars nervosa, of the hyaline bodies, 

 or the disintegrating pars intermedia cells. 



Gcetsch has recently ascertained, as the result of numerous experiments, 

 that extract of anterior lobe of pituitary body (representing pituitrinum 

 glandulare), when fed to young rats, has a stimulating effect upon the growth 

 of the animal and upon its sexual development and activity. Posterior lobe 

 extract (representing pituitrinum infundibulare), when given in the same 

 manner, has a retarding influence. 



Oppenheim calls attention to the fact that both tabes and general paralysis 

 may be closely simulated by pathological processes affecting the hypophysis. 

 Among the effects of such processes may be a simple optic atrophy and 

 evidences of true posterior column degeneration. These symptoms have 

 nothing to do with the presence of the tumor per se, that is, they are not due 

 to pressure, for instance, nor are they due to a true tabetic or paretic process, 

 but are due to the alteration (quantitative or qualitative) of function of the 

 ductless glands. 



REFERENCES 



Gushing (H.}. Pituitary body and its disorders. Phila. and London, J. B. Lippincott 

 Co., 1912. 



Gushing (H.). Concerning the symptomatic differentiation between disorders of the 

 two lobes of the pituitary body; with notes on a syndrome accredited to hyperplasia of the 

 anterior and secretory stasis or insufficiency of the posterior lobe. Am. J. M. Sc., March, 



1913, PP- 313, 328. 



v. Frankl-Hochwart (L.}. Die Diagnostik der Hypophysistumoren ohne Akrome- 

 galie. Wien. med. Wcnsch., 1909, 37, p. 2127, 38, p. 2297, 39, p. 2326, 1909, 37, p. 

 2127, 38, p. 2257. 



Wolf stein (D. J.}. Tumor and clinical pathology of the hypophysis. Lancet- 

 Clinic, Vol. CVIII, Oct. 5, 1912, pp. 365-373. 



Sweet (J. E.} and Allen (A. R.}. The effect of removal of the hypophysis in the 

 dog. Annals of Surgery, 58, 1913, p. 485. 



Herring (P. T.). The physiological activity of the pars intermedia and pars nervosa 

 of the ox pituitary quantitatively compared. Quarterly journal of Physiology, Vol. VIII, 

 19, pp. 267-274. 



GcEtsch (.E.). The influence of pituitary feeding upon growth and sexual develop- 

 ment. An experimental study. Bulletin of the Johns Hopkins Hospital, Vol. XXVII, 

 No. 300, Feb. 1916, p. 29-50. 



Oppenheim (H.). Uber Vortaiischung von Tabes und Paralyse durch Hypophysis- 

 tumoren (Pseudotabes pituitaria, etc.). Ztschr. f. d. ges. neurol. u. psychiat., i, 1914, 



xxv, pp. 527-535- 



