438 THE DISEASES OF THE SEXUAL GLANDS 



G. Pommer has upheld the view that both diseases depend on an affection 

 of the central nervous system. Considering the intimate relationship 

 between the central nervous system and the function of the ductless glands 

 this supposition seems to me to deserve more attention than it has thus 

 far found. 



Addendum 



Whitehead reports the histological examination on the testicle of the 

 case of E. M. Prince. As Prince's case is. very interesting and apparently 

 forms the only case on record of true human hermaphroditism in which the 

 organs of both sexes were present, it will be quoted in extenso: 



The patient, apparently a girl, eighteen years of age, consulted Prince 

 stating that she had never menstruated, and that she suffered from headaches 

 supposed to be due to that fact; she had withdrawn from the college she had 

 been attending because of the headaches which were worse about every 

 twenty-eight days. She appeared to be a healthy, robust girl, refined 

 and intelligent. There was a heavy growth of hair upon the head, the 

 voice was soft and feminine and the breasts well developed, rather larger than 

 ordinarily seen in a girl of her age. The hips were typically feminine, the 

 mons Veneris was rather scantily covered with hair, the labia majora were 

 normal; the clitoris was not enlarged and the hymen was unruptured. No 

 uterus could be made out by rectal examination. The vagina was about 2 in. 

 long, and terminated in a blind pouch. In the upper part of each labium 

 majus a body could be felt which was freely movable. The diagnosis made 

 was congenital abscess of the uterus with hernia of both ovaries. At the 

 operation (exploratory laparotomy) a small body the size of a pecan nut was 

 found at the usual site of the uterus, and to the left of this there was found an 

 apparently normal ovary with a rudimentary tube. At a subsequent opera- 

 tion the two bodies in the labia majora were removed and were found to be 

 testes, a diagnosis which was afterward confirmed by a pathologist. 



In this case the secondary sexual characters were of the female type. 

 A weak point in the case is the absence of the microscopical examination of 

 the bodies believed to be ovaries. 



Saenger reports seven cases of eunuchoidism which had come under his 

 personal observation, and concludes that the condition is by no means so 

 rare as is generally supposed. His last case is especially interesting in that 

 the subject was an kyphoscoliotic acromegalic individual aged thirty-three 

 years, who developed a late eunuchoidism in consequence of a gangrene of 

 the testicle; after the injury there was a failure of potency, a falling-out of 

 the hairs of the beard and pubic regions and in part also of the eyebrows 

 but there was no eunuchoidal distribution of fat, nor gigantism. 



All references to the subject of the sexual glands would be incomplete 

 without mention of the name of Leo Loeb, whose researches on the function 



