INFANTILISM 469 



veloped in the new-born. At the same time, the remaining behind of the 

 development of the sexual glands in infantilism is only a subordinate symp- 

 tom of the entire clinical picture. We therefore do not find in infantilism 

 such profound developmental disturbances as in eunuchoidism. The 

 genitalia are quite childish and the sexual glands functionate like the sexual 

 glands of children, while in eunuchoidism the sexual glands eventually do 

 not functionate at all or slight islands of the sexual gland tissue have 

 developed further, corresponding with the age, whereby there occurs an en- 

 tirely insufficient function, a function that, on account of the faulty develop- 

 ment of the accessory apparatus, is lacking; thus we see that the sexual glands 

 onnfantilism or the infantile genitalia are essentially different from those of 

 eunuchoidism. 



Thus if true infantilism comers about through the standing-still of the 

 whole organism at a juvenile stage of development, the ductless glandular 

 system remains Justus childish as the skeleton or the hematopoietic apparatus 

 or the central nervous system; therefore the inhibition of the ductless glandu- 

 lar system is only coordinated with that of the entire organism; as, if these 

 premises hold good, we are not justified in classing infantilism with the 

 primary ductless glandular diseases; on the other hand, it does not then seem 

 to me justifiable to designate as infantilism sharply delimited clinical pictures 

 that depend on a primary disease or developmental disturbance of a definite 

 ductless gland, pictures such as juvenile myxedema, juvenile hypophysial 

 dystrophy, or eunuchoidism. 



Before I enter into the symptomatology of true infantilism and the basis 

 of the view just expressed, I would like to report some typical cases of true 



infantilism. 







Observation LVI. J. H., twenty years old. At the age of seven years, commotio 

 cerebri through fall from a tree. Present manifestations of a benign pyloric stenosis with 

 dilatation of the stomach and hypersecretion. For one-half year tetany. 



Total length, 142^ cm.; lower length, 69 cm.; span width, 143 cm. 



The patient looks like a boy thirteen years old. Facial expression and psychical at- 

 titude entirely childish. Abundance of hair on head. Beard hair absent, hair in the 

 axillae and on the mons Veneris absent, soft downy hair on face. Penis small. Both 

 testicles small. No libido, rarely weak erections which have appeared only recently, no 

 ejaculations. The epiphysial junctures of the skeleton of the hand are almost all still open. 

 For two years tetany, at the close of which slight manifestations of hyperthyrosis. 



Observation LVII. W. K., eight years old. Entrance into the clinic Nov., 1910. At 

 the age of four years gradual deterioration of the gait. The child also remained backward 

 mentally, and repeated for the third time his first class in school. 



Typical progressive muscular atrophy, the description of which we may omit here. 



Typical length, 117 cm. Circumference of head, 51 cm. Circumference of breast, 57 

 cm. Circumference of abdomen, 55 cm. From coracoid process to olecranon 25.5 cm. 

 From iliac spine to internal malleolus 56 cm. 



Both lobes of the thyroid distinctly palpable. 



The tongue is large, always is seen to a certain extent between the teeth. Root of 



