494 



VEGETATIVE DISTURBANCES 



Another form of micromelic growth disturbance, osteoporosis congenita 

 (Kundraf), is characterized by a disturbance of the epiphysial as well as peri- 

 osteal bone formation. Clinically, it has up to the present been without 

 significance as the infants have never been capable of maintaining life; ex- 

 cept that Hagenbach described a dwarf with tumor of the hypophysis, 

 whose bone alterations Hagenbach regarded as osteoporosis. Up to the pres- 

 ent there are no tenable relationships between this disease and the ductless 

 glandular system. 



V. MONGOLISM 



(Mongoloid Idiocy} 



Mongolism was first recognized as a disease sui generis by Langdon-Down. 

 I shall here limit myself to a short delineation, paying especial attention to 



FIG. 93. Six and one-half-year old girl (Mongolism) with three-year-old healthy sister. 



the differential diagnosis from infantile myxedema, in the course of which 



I follow the excellent descriptions of Bourneville, Kassowitz, Scholtz, and Siegert. 



Symptomatology.- The Mongoloid children show a great family likeness. 



The term Mongolism is used because the physiognomy of these children shows 



