538 DISEASES OF THE INSULAR APPARATUS OF THE PANCREAS 



into account the difference in body weights of the normal persons and 

 diabetics they investigated. I here quote in descending series the body 

 weights of the normal individuals and the diabetics. 



Normal individuals: 83.5-79.7-74.4-67.6-66.5-66.0-59.6-48.5. 



Severe diabetics (weight during the experiment): 67.1-59.0-54.9-52.7- 

 51.8-48.8-48.0-40.5. 



A glance at this summary shows the great difference in body weight 

 between the normal and the diabetic individuals. 



When we compare with one another the heat production of those cases 

 that have the same body weight, we obtain the same result that I found in 

 the preceding experiments. This is seen in the following summary: 



Mrs. B. Diabetic G 



Weight 67.0 67.0 



Height 161.0 178.0 



Calories per kg. per hr i .09 1.15 (bed calorimeter) 



L.E.E. Diabetic F 



Weight 59.6 59.0 



Height I79-Q 176.0 



Calories per kg. per hr i-47 I -39 



Dr. R. Diabetic A 



Weight 48.5 48.8 



Height 167.0 171.0 



Calories per kg. per hr i .39 i .34 



The heights of the persons under experimentation are not entirely alike. 

 In the cases of Mrs. B. and diabetic G the difference is indeed appreciable. 

 In the other two pairs the difference would not signify much. In addition, 

 in one case the difference favors the normal individual, in the other it favors 

 the diabetic. We see from this summary that the heat production in cases of 

 severe diabetics does not differ essentially from that of the equally heavy normal 

 individual. 



Benedict and Joslin themselves made the objection that their material 

 is not uniform in respect to body weights. They sought to rule out this 

 objection in the following experiment (Case C. S., 227). The first investiga- 

 tions were undertaken at a time that the patient weighed 62.4 to 65.4 kg. 

 They found at that time a heat production between 1.23 and 1.40 per kilo- 

 gram per hour. As the patient had later fallen away to 54.9 kg., the heat pro- 

 duction (in one experiment) was 1.26 per kilogram per hour. I can ascribe 

 to this one experiment no demonstrative value. It is a known law that in 

 normal individuals the exchange lies higher the smaller and lighter the indi- 

 vidual is. This is readily seen [from the figures that Benedict and Joslin 

 themselves have summarized. 



