THE PROBLEM OF PATTERN n 



parts in the organism. It is necessary to make the dis- 

 tinction clear between organismic and protoplasmic 

 correlation. I have already pointed out that organismic 

 pattern is of a different order of magnitude from pro- 

 toplasmic pattern, and if we admit this it is evident that 

 organismic correlation consists in the relations between 

 different molar regions which may be separated by 

 measurable and often very considerable differences. 

 Chemical reaction between two protoplasmic constitu- 

 ents, adsorption upon a colloid particle, the attraction 

 or repulsion between ions or ionized colloid particles, 

 these and similar relations considered individually are 

 factors in protoplasmic rather than organismic correla- 

 tion, but these same processes occurring in an orderly 

 way in sufficient quantity may become organismic. 

 Organismic correlation is concerned with masses of pro- 

 toplasm, cells, molar regions and organs, with the 

 production of substances in mass, their transportation 

 over directly measurable and often considerable dis- 

 tances and their action upon regions and organs as 

 wholes, and with the transmission of dynamic changes, 

 also over directly measurable and often considerable 

 distances. The particular physicochemical processes 

 involved in organismic correlation are of course proto- 

 plasmic processes, but the mass, the order, and the 

 distances concerned are of a different order of magnitude 

 from those concerned in strictly protoplasmic relations. 

 At the boundary line between organism and protoplasm, 

 if such a line exists even in the simplest living individuals, 

 there may be difficulty in distinguishing between proto- 

 plasmic and organismic correlation, but nowhere else is 

 this the case. The house represents a pattern, an 



