DISEASES PRODUCED BY DISTILLERY AND SUGAR FACTORY PULP. 261 



suffering from a cerebral tumour. It also shows hyperaesthesia, slight 

 colic, and sensitiveness of the abdomen. 



In sheep the symptoms consist in alternate extreme depression and 

 extreme excitability. 



In both species the termination is always rapid : death occurs in a 

 few^ days. 



The abdominal lesions are identical with those of the acute form. 

 They consist in gastro-enteritis, or, rather, intense congestion of the 

 abomasum and intestine, with extravasation of blood around the acini 

 of the glands and beneath the mucous membrane, etc., and in more or 

 less marked desquamation of epithelium. 



The annexed organs sometimes present secondary changes : in the 

 nervous centres the lesions are more marked ; the meninges are con- 

 gested, in some cases inflamed, and cerebro-spinal fluid is present in 

 increased quantity. 



Subacute or Chronic form : Symptoms. This form is equally 

 frequent in the ox and sheep ; it develops insidiously, and for a time 

 may escape detection. 



The symptoms are those of slight gastro-enteritis without tympa- 

 nites; but this condition is succeeded by serous, foetid, uncontrollable 

 diarrhoea, which weakens the animal and causes death from excessive 

 wasting and hydr?emia. 



The sensitiveness of the entire right side of the abdomen, the special 

 diarrhoea, the cardiac disturbance, and the widely-distributed oedema, 

 usually suffice to prevent confusion with the ordinary forms of gastro- 

 enteritis. In sheep the diarrhoea is blackish, sometimes blood-stained, 

 and is accompanied by a sub-icteric or icteric tint of the mucous mem- 

 branes, of the skin, and of all the tissues. The intensity of coloration 

 affords a guide to the rapidity of development of the disease. The urine 

 is also bile-stained, and there appears to be an exchange of functions 

 between the two great depurative organs, the liver and kidney. The 

 urine may become sanguinolent, because it contains either unchanged 

 blood or simply dissolved haemoglobin. 



The lesions are similar to those previously described, but with 

 modifications of intensity. When diarrhoea has been marked and per- 

 sistent, the digestive mucous membrane is hardened, indurated, and 

 appears as though tanned. This is due to chronic inflammation, 

 probably to the gastro-enteritis with which the condition begins. The 

 liver appears as if cooked ; the fat, the majority of the tissues, and 

 especially the conjunctiva, exhibit a light yellow tint, pointing to hepatic 

 disturbance. 



The diagnosis is generally easy in all three forms, provided that 

 the food be examined. 



