228 THE VETERINARY SCIENCE 



the normal. The maximum temperature is reached in from 

 fifteen to eighteen hours. It does not become normal until 

 after twenty-four to forty-eight hours. During this time the 

 animal is very decidedly ill. The tumor at the point of 

 injection increases in size for two or three days, and only 

 disappears after several days. In a healthy horse, on the 

 contrary, mallein in even much larger doses has no apprecia- 

 ble constitutional effects. A small edematous swelling is 

 formed at the site of injection, which is hot and slightly 

 sensitive early, but soon diminishes in size and in about 

 twenty-four hours entirely disappears. 



It is essential that the mallein be used as soon as the 

 package is opened. 



The site of the injection (preferably the side of the neck) 

 should be carefully shaved and disinfected, a 5-per-cent solu- 

 tion of carbolic acid, or a 1 to 1000 solution of bichloride of 

 mercury being used for this purpose. Careful sterilization of 

 the syringe should be made before and after the injection, as 

 directed. Mallein, as well as the syringe, can be secured 

 from the Detroit Instrument Co., Detroit, Mich. 



II. — Fevers. 



These are four in number, as follows: Influenza, Pur- 

 pura Hemorrhagica (commonly known as Button Farcy), 

 Strangles or Distemper, Epizootic Cellulitis (Pink Eye). 



1. Influenza. 



This disease received its name when, at one time, it was 

 thought to be influenced by the stars. It is very common 

 among horses of America, and is a disease that is liable to 

 affect any organ of the body. 



Causes. — The germs of influenza float about in the air 

 and in this manner is quickly communicated from one horse 

 to another. It is more common in the spring and fall, when 

 the horses are shedding their coats, than at any other time of 

 the year. In 1874 and 1878 it -broke out in the form of a 

 regular epizootic, and spread all over the country, causing a 

 great deal of trouble. Horses that are kept in badly-ven- 

 tilated stables, especially those that are underground, are 

 more subject to it. 



Symptoms. — Among the first symptoms are a dull, lan- 

 guid appearance, a tendency to sweat upon the slightest 



