Syini)toins. 69 



figurement in the form of thick, sometimes cartilage-like 

 cicatrices. 



In some cases an erysipelatous endocarditis develops after 

 the disappearance of the eruptions which terminates fatally, 

 or a paralytic condition results which may remain for a longer 

 time. 



Jensen (1891), Lorenz, Liipke and others found in urticaria the 

 erysipelas bacillus in the lymph spaces of the affected parts; on the 

 other hand, Markus succeeded in producing a verrucose endocarditis 

 as well as kidney infarcts in a pig by intravenous injection of 2 cc. 

 of a bouillon culture which was derived from a dermatitis, while 

 Schiitz observed urticaria in ordinary country hogs and erysipelas in 

 English breeds after the injection of the same culture. Jensen and 

 Lorenz proved the presence of the erysipelas l)acillus in the lymph spaces 

 of the chorion to be a cause of dry gangrene. 



2. Erysipelas septicemia. In this, the most frequent form 

 of the disease, the animals suddenly cease to root and to run. 

 They lie exhausted and dull upon the ground, they crawl under 

 the straw in the stall and wdien caught they do not squeal or 

 show the usual resistance. They show inappetence, nausea and 

 vomiting. The body temperature rises even at the onset very 

 high (up to 41° to 42° C.) and remains practically constant. 

 The eyelids are frequently edematously swollen, the conjunctiva 

 is injected, the canthus of the eye is filled wdth a slimy secre- 

 tian. At first there is constipation, later, however, diarrhea 

 appears, when the animals pass frequently soft, mushy, later 

 entirely fluid stools, which are light gray or dark brown from 

 the admixture of blood. 



On the second day, rarely earlier, or only immediately 

 before death the characteristic reddening of the pkin appears 

 on various parts of the body. On the abdomen, the inner sur- 

 face of the thighs, in the axillary region, sometimes also on 

 the neck and ears, various sized, irregular, pale red spots 

 appear, which later take up a darker and brighter color, and 

 confluate. The skin over the affected areas is only slightly 

 swollen if at all, and not painful. The redness disappears when 

 pressure is applied but returns when it is removed. In a few 

 cases hempseed sized vesicles containing a serous fluid de- 

 velop on the surface of the spots which later dry and form 

 brownish crusts. Exceptionally gangrene of the skin is ob- 

 served in some parts, especially on the ears, nose and the point 

 of the tail. 



In severe cases in addition to the described symptoms there 

 are weakness of the hind quarters, cyanosis of the mucous 

 membranes as ^vell as manifestations of pulmonary edema. As 

 the symptoms become more progressive, a sudden drop of tem- 

 perature follows, and finally the animals die in 3 to 4 days. 

 Exceptionally death results at the end of the first day or tlien 

 only after 8 to 9 days. In milder cases the intensity of the 



