Treatment, Prevention. 349 



with corrosive sublimate, see p. 229, powdered oxide of zinc, 

 etc.). Boru recommends placing oakum balls sprinkled with 

 alum between the hoofs, Pilger painting the ulcerations on the 

 hoofs with a 10% bacillol ointment, in severe cases the appli- 

 cation of bacillol cataplasms. 



Complications which result from improper treatment, or 

 from unfavorable external influences should be treated in ac- 

 cordance with surgical rules. 



In atfections of the udder, first of all regular milking, if 

 possible with milk catheters, is necessary. In addition to this 

 washing with luke warm water, or with a 2% boracic acid 

 solution, is sufficient. If the inflammation is more intense, and 

 the sensitiveness is greatly increased, it is advisable to apply 

 warm applications to the sores, after previously softening and 

 loosening the scabs, also lead or zinc ointment, lanolin, boracic 

 acid vaseline (20%), or dermatol vaseline; tincture of opium 

 may be added to the salves, or a 5% cocaine salve may be used 

 from the beginning. Rubbing with glycerin gives likewise good 

 results. Parenchymatous inflammation of the udder is best 

 treated with inunctions of green soap, containing tincture of 

 iodine (1:10), or camphor ointment (1:1), repeated twice daily 

 for 10 minutes at a time, and in order to prevent the formation 

 of strictures the udders should be milked out every 2 to 3 hours. 

 During the intervals iodoform bougies may be introduced into 

 the milk ducts (Born). 



In malignant forms of the disease it is advisable to watch 

 the activity of the heart in the affected animals carefully, espe- 

 cially from the fifth to the ninth day, and in case its function 

 is disturbed, the threatening heart depression should be treated 

 by stimulation. In case of severe symptoms the early slaughter 

 of the animals is indicated. 



In 1901, Baccelli warmly recommended intravenoiis injections of corrosive 

 sublimate (0.05:0.1 g. in ]ihysiological salt solution). According to later experi- 

 ences this treatment is useless, sometimes even dangerous. It has no favorable 

 influence on the local lesions, nor does it influence the course of the disease favor- 

 ably, and further poisoning was occasionally observed in the treated animals, which 

 sometimes failed to appear until 3 to 4 weeks later (Sacchini, Lanzillotti-Buonsanti, 

 Lciffler). The treatment with intravenous injections of collargol (1% solution), 

 which has been recommended by Winkler, was in the comparative experiments of 

 Barabas found to have no favorable influence on the course of the disease, and 

 to be incapable of preventing it. 



Perroncito recommends his Hamoaphthin for the treatment of aS'ecte(\ cattle 

 which he prepares as follows: blood which is taken from recovered cattle, that 

 have been repeatedly treated with filtered lymph, is defibrinated, filtered through 

 hydrophylic cotton, and mixed with 3 to 4% sulphuric ether, and 0.75% formol. 

 After the injection of this preparation (0.5 to 1 g. per kg. body weight), which 

 keeps for a long time, the recovery is supposed to be almost instantaneous (?). 



Prevention. The highly contagious character of foot-and- 

 mouth disease, and the fact that the infection is not only trans- 

 mitted by living animals, but also by the most varied objects, 

 render its control at the time of its prevalence very difficult. 

 Nevertheless it has recently been observed that outbreaks which 

 have not yet spread very extensively may be eradicated by 



