(306 TubeiT-ulosis. 



Cbl. f. Bakt., 1097. XLIV 4(53; IPOO. LIT. 380. — Calmette & Gu^Rix. A. P., 1905. 

 XIX. 601; 1906. XX. 353 u. 6(i9. — Ostertag, Breidert, Kaestner & Kraut- 

 STRUNK, Arb. d. hyg. Inst. d. tierari^tl. Ils-ch. Berlin, V. H. 1905 (Lit. on Diagnosis). 



— Pearson & Gillilaxd, J. of comp. Path., 1905. XYIII. 207. — Koch, ScHfxz, 

 Neupeld & MiESSNER, A. f. Tk., 1905. 545. — Moussu, Eec, 1905. 777; 1907. 701. 



— Heymans, Arch, internat. de pharniafodvnaniie, 1905 — 1910. XYII — XX. — 

 Meyer, Z. f. Tni., 1906. X. 241. — Fischer,' Ibid., 1906. X. 82 (Lit. on Uterustub.). 



— HuTYRA, Z. f. Tin., 1907. XI. 241. — Pirquet, Yakzination \i. vakz. Allergie. 

 Wien 1907. — Weber & Titze. Tbk.-Arb. d. G.-A. 7., 9. u. 10 H. 1907, 1908 u. 

 1910 (Lit. on Ininumization). — Yallee, Bull., 1907. ISO; Eev. gen., 1908. XI. 

 318; 1909. XTIL 355; A. P., 1909. XXYII. 585. — LigniJires, Bull., 1908. 112 u. 

 517; 1909. 146. — Mohler & Washburn, An. Ind., 1907. 215. — Schroeder & 

 Cotton, An. Ind., Bull. Nr. 99. — Much, Beitr. z. Kl. d. Tb., 1907. YIII. 85; 

 19C8. XI. 175. — Wyssmann, Scliw. A., 1908. L. 90 (Lit. on Tub. after Contrac- 

 tion). — Titze & Weidanz, Tbc.-A. d. G.-A., 9. H., 1908. — Mayer, Diss. Bern. 19(IS 

 (Lit. on sheep tul).). — Calmette & Guerin. A. P., 1908. XXII. 1. — Klimmer, 

 Z. f. Tm., 1908. XIL 81. — Klimmer & Kiessig, Monh., 1908. XX. 97; Z. f. Tni., 

 1909. XIII. 313. — Eomer, Z. f. Infkr., 1909. YI. 393, — Joest. Ibid., 1909. Y. 

 224. Aa. 257; 1910. VII. 131. — Albien, Z. f. Tni., 1909. XIII. 109 (Lit. on Con- 

 genial Tub.). — Bongert, a. f. Hyg., 1909. LXIX. 263. — Forster, Cbl. f. Bakt., 

 1909. LI. 417 (Lit. on sterlization' of milk.). — Henschel, Diss. Bern. 1909 (Lit. 

 on anatomical statistics). — Wolff-Eisner, Friihdigan. u. Tbc.-Imm. Wiirzburg 

 1909. — Richter, Z. f. Infkr., 1909 V. 243 (Lit. on local reaction). — Joseph. B. 

 t. W., 1909. 847. — GoEDECKE, Tbc. d. Pferdes, Hannover, 1909. — Flugge, 

 Yerbreitungsw. u. Bekampfg. d. Tub. Leipzig. 1908. — Nowak, Z. f. Infkr., 19(i9. 

 VI. 313 (Lit. on immunization). 



Tuberculosis in Man. At the present day tuberculosis is 

 the most destructive disease of mankind, estimates showin^a^ 

 that one-seventh of all deaths, and one-third of all deaths 

 occurring during tlie "working age" of human beings, are due 

 to this disease. 



In the majority of cases it manifests itself as a chronic 

 destructive affection of the lungs (consumption, phthisis 

 puhnonum). In cases where the disease appears primarily as 

 an affection of the peripharyngeal and cervical lymph glands, 

 the digestive organs or the bones, the development of puhnonary 

 tuberculosis is usually only a question of time. In a certain 

 number of cases the disease confines its entire course to the 

 abdominal organs (alxlominal hanpli glands, especially in 

 children). In exceptional cases the disease terminates as a 

 generalized acute miliary tuberculosis. 



As has been found to be the case in animals, man also 

 with few exceptions acquires the disease in extra-uterine life. 

 Infection is caused as a rule ])y the human type of tubercle 

 l)acilhis which is disseminated in large quantities by diseased 

 human beings, particularly through the medium of expectorated 

 secretions from the lungs. The bacilli are then inhaled or 

 ingested by persons that come into contact with the patients, 

 particularly when they live Avith them in the same close, dirty 

 and poorly ventilated dwellings. 



The virus of animals, and especially that of bovine tuber- 

 culosis plays a less important role in the infection of man. 

 Experimental investigations of recent years have shown, how- 

 ever, that man is susceptible to infection with bovine virus. 

 This has been demonstrated by well authenticated cases where 

 human beings became affected after consumption of milk from 



